Tirzepatide is a synthetic 39-amino acid linear peptide that acts as a dual agonist at the glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. It is commonly studied in metabolic research, incretin pathway modulation, and energy homeostasis models.
Supplied as a high-purity lyophilised powder for laboratory investigation. The C20 fatty diacid modification enhances albumin binding and prolongs half-life in experimental settings.
Key Features
- High purity ≥98–99% (HPLC verified)
- 30mg per vial
- Lyophilised for stability
| Compound | Tirzepatide (Dual GIP/GLP-1 Receptor Agonist) |
| Form | Lyophilized white to off-white powder |
| Amount per vial | 30 mg |
| Purity | ≥98% (HPLC verified) |
| Amino Acid Length | 39 amino acids (with C20 fatty diacid modification) |
| Molecular Formula | C₂₂₅H₃₄₈N₄₈O₆₈ |
| Molecular Weight | 4813.53 g/mol |
| CAS Number | 2023788-19-2 |
| Solubility | Soluble in bacteriostatic water after reconstitution |
| Storage (lyophilized) | –20°C, protected from light and moisture |
Lyophilized Storage
Store unopened vials at –20°C in a dry, dark environment, protected from light and moisture. When stored correctly, the lyophilized powder is stable for up to 24–36 months.
Reconstitution Instructions
- Use sterile bacteriostatic water (BAC water) for reconstitution.
- Recommended volume: Add 2–5 mL of BAC water slowly along the side of the vial to achieve desired concentration (e.g., 6–15 mg/mL).
- Gently swirl or tilt the vial until the powder is fully dissolved. Do not shake vigorously to avoid foaming or degradation.
- Once reconstituted, the solution should be clear and colorless to slightly hazy.
- Store the reconstituted solution in a refrigerator at 2–8°C and use within 28 days.
Handling Notes
- Always work in a sterile environment and use aseptic technique.
- Avoid repeated freeze-thaw cycles.
- Protect from direct light and excessive heat during experiments.
- Discard any unused solution if it becomes cloudy or contains visible particles.
Note: Typical experimental concentrations and protocols vary widely by study design. Follow your laboratory’s standard operating procedures.
Commonly studied in research involving glucose-dependent insulinotropic signalling and metabolic regulation.
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